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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPS27
All Species:
30
Human Site:
S218
Identified Species:
82.5
UniProt:
Q92552
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92552
NP_055899.2
414
47611
S218
P
G
L
K
Q
K
N
S
V
G
F
S
S
Q
L
Chimpanzee
Pan troglodytes
XP_517715
414
47651
S218
P
G
L
K
Q
K
N
S
V
G
F
S
S
Q
L
Rhesus Macaque
Macaca mulatta
XP_001098829
414
47944
S218
P
G
L
K
Q
K
N
S
V
G
F
S
S
Q
L
Dog
Lupus familis
XP_852973
452
51511
S218
P
G
L
K
Q
K
N
S
V
G
L
S
S
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BK72
415
47776
T218
S
G
L
K
Q
R
N
T
V
G
L
S
S
Q
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512710
457
52310
T255
P
G
L
K
Q
E
N
T
V
G
W
S
S
R
L
Chicken
Gallus gallus
XP_424803
407
46722
T215
T
G
L
K
Q
T
S
T
V
G
F
S
S
Q
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003778
398
45789
S219
A
G
L
K
Q
E
N
S
I
G
F
S
A
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799111
372
42538
R199
T
L
A
D
A
S
R
R
V
D
G
I
L
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.1
75.4
N.A.
76.3
N.A.
N.A.
58.8
64.4
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
28.7
Protein Similarity:
100
99.7
96.1
82.9
N.A.
86.7
N.A.
N.A.
74.4
81.1
N.A.
69.5
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Identity:
100
100
100
93.3
N.A.
73.3
N.A.
N.A.
73.3
73.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
100
86.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
12
0
0
0
0
0
0
0
12
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
56
0
0
0
0
% F
% Gly:
0
89
0
0
0
0
0
0
0
89
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% I
% Lys:
0
0
0
89
0
45
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
89
0
0
0
0
0
0
0
23
0
12
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
78
0
0
0
0
0
0
0
0
% N
% Pro:
56
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
89
0
0
0
0
0
0
0
0
67
0
% Q
% Arg:
0
0
0
0
0
12
12
12
0
0
0
0
0
23
0
% R
% Ser:
12
0
0
0
0
12
12
56
0
0
0
89
78
0
0
% S
% Thr:
23
0
0
0
0
12
0
34
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
89
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _